About the Lab
Who we are:
Dr. Kyra Campbell
PI and Sir Henry Dale Fellow
I have long been fascinated by the question of how cells assemble into functional tissues at both the subcellular and intercellular levels. After studying Natural Sciences at the University of Cambridge and being fired up by my final year course in Developmental Biology, I stayed on to do my PhD with Prof. Helen Skaer. In close collaboration with Prof. Elisabeth Knust, I explored how cell polarity is established and maintained as cells undergo the extensive remodelling that underlies tissue morphogenesis. For my postdoctoral training, I moved to the lab of Prof. Jordi Casanova in Barcelona, and focused on developing a novel model system for studying the mechanisms underlying cell plasticity during development, and in collaboration with Eduard Batlle’s lab at the IRB, in tumourigenesis. In 2017 I activated a Sir Henry Dale Fellowship that I was awarded by the Wellcome Trust/ The Royal Society, and started my group in the University of Sheffield.
contact:
[email protected]
PI and Sir Henry Dale Fellow
I have long been fascinated by the question of how cells assemble into functional tissues at both the subcellular and intercellular levels. After studying Natural Sciences at the University of Cambridge and being fired up by my final year course in Developmental Biology, I stayed on to do my PhD with Prof. Helen Skaer. In close collaboration with Prof. Elisabeth Knust, I explored how cell polarity is established and maintained as cells undergo the extensive remodelling that underlies tissue morphogenesis. For my postdoctoral training, I moved to the lab of Prof. Jordi Casanova in Barcelona, and focused on developing a novel model system for studying the mechanisms underlying cell plasticity during development, and in collaboration with Eduard Batlle’s lab at the IRB, in tumourigenesis. In 2017 I activated a Sir Henry Dale Fellowship that I was awarded by the Wellcome Trust/ The Royal Society, and started my group in the University of Sheffield.
contact:
[email protected]
Dr. Andrew Plygawko
Postdoc
My primary interests lie in how asymmetry is established and maintained in biological systems, and how that asymmetry leads to the birth and future function of complex organs. I studied for my Bachelors and Masters degrees at Durham University, where I was struck by the complexity of cell architecture and the cytoskeleton. I then moved to the Gurdon Institute at the University of Cambridge, where I joined the St Johnston lab to study cell polarity establishment and mRNA localisation in the Drosophila egg chamber. Following the completion of my PhD studies I joined the Campbell lab, where I am working on the coordinated migration and assembly of the embryonic midgut epithelium.
contact:
a[email protected]
Postdoc
My primary interests lie in how asymmetry is established and maintained in biological systems, and how that asymmetry leads to the birth and future function of complex organs. I studied for my Bachelors and Masters degrees at Durham University, where I was struck by the complexity of cell architecture and the cytoskeleton. I then moved to the Gurdon Institute at the University of Cambridge, where I joined the St Johnston lab to study cell polarity establishment and mRNA localisation in the Drosophila egg chamber. Following the completion of my PhD studies I joined the Campbell lab, where I am working on the coordinated migration and assembly of the embryonic midgut epithelium.
contact:
a[email protected]
Dr. Joanne Sharpe
Postdoc
I was first introduced to the idea of using fruit flies in scientific research during my integrated Masters at the University of York. There I worked with Prof Sean Sweeney on a Drosophila model of lysosomal storage disease, and became motivated to continue to use flies to better understand cellular function and dysfunction in human health and disease. In 2017, I started a PhD in molecular neuroscience at the University of Manchester, supervised by Prof Stuart Pickering-Brown and Dr Ryan West. During my PhD I developed novel Drosophila models of frontotemporal dementia and amyotrophic lateral sclerosis linked to the C9orf72 mutation. In 2021, I moved to the Sheffield Institute of Translational Neuroscience to work in the West lab, continuing to dissect the molecular mechanisms underpinning neurodegeneration using these models. In 2022, I joined the Campbell lab, focussing on the adult midgut and the role of epithelial-to-mesenchymal transition in cancer development and metastasis.
contact:
[email protected]
Postdoc
I was first introduced to the idea of using fruit flies in scientific research during my integrated Masters at the University of York. There I worked with Prof Sean Sweeney on a Drosophila model of lysosomal storage disease, and became motivated to continue to use flies to better understand cellular function and dysfunction in human health and disease. In 2017, I started a PhD in molecular neuroscience at the University of Manchester, supervised by Prof Stuart Pickering-Brown and Dr Ryan West. During my PhD I developed novel Drosophila models of frontotemporal dementia and amyotrophic lateral sclerosis linked to the C9orf72 mutation. In 2021, I moved to the Sheffield Institute of Translational Neuroscience to work in the West lab, continuing to dissect the molecular mechanisms underpinning neurodegeneration using these models. In 2022, I joined the Campbell lab, focussing on the adult midgut and the role of epithelial-to-mesenchymal transition in cancer development and metastasis.
contact:
[email protected]
Dr. Jamie Adams
Postdoc
I am a motivated young scientist with interests in both developmental and cancer biology, with a particular focus on mechanisms involved in metastatic events, such as epithelial-mesenchymal transition (EMT). I previously studied Biochemistry at Sheffield Hallam before coming to the University of Sheffield to study a Masters in Molecular Medicine. During my MSc studies, I performed research on the metalloprotease ADAMTS5 and whether this protein played a role in the enhanced-invasive phenotype witnessed in Rab25-upregulating ovarian cancer cells. After successfully defended my thesis in Nov 2022 I have been continuing my work as a Postdoc in the Campbell lab.
contact:
[email protected]
Eddie Shohei Kan
PhD Student
I completed my undergraduate studies at the Department of Molecular Biology and Biotechnology at the University of Sheffield and continued on to a integrated Masters program with a industrial placement at GlaxoSmithKline, under the Adaptive Immunity Research Unit. During my PhD project, I will be working on mechanisms underlying Epithelial to Mesenchymal transition (EMT).
contact:
[email protected]
Eddie Shohei Kan
PhD Student
I completed my undergraduate studies at the Department of Molecular Biology and Biotechnology at the University of Sheffield and continued on to a integrated Masters program with a industrial placement at GlaxoSmithKline, under the Adaptive Immunity Research Unit. During my PhD project, I will be working on mechanisms underlying Epithelial to Mesenchymal transition (EMT).
contact:
[email protected]
Jason Morgan
PhD Student
I have spent the last five years working as a secondary school teacher and I am currently volunteering in the Cambell lab. I have a masters in Neuroscience with a focus on neurodegenerative diseases, and I am particularly interested in using disease as a tool to better understand the healthy function of a cell, and hence look for new treatments. I am looking to undertake a PhD and restart a career in research, and I am using this opportunity to widen my knowledge of other areas of biomedical science.
contact:
[email protected]
Zack Richards
PhD Student
I did my Undergraduate degree in Biochemistry and followed this up with a Masters in Medical and Molecular Biosciences both at Newcastle University. Understanding the general processes underlying cell biology and the changes they undergo was a theme of constant interest for me during my studies and after a few years in laboratory-based work I have now begun a PhD in the Campbell lab at the University of Sheffield looking at cell migration in the gut of Drosophila embryos where I hope to be able to better understand the mechanisms responsible through experimental and computer-based techniques.
contact:
[email protected]
Previous Lab members
Nicholas Nisbet
Mphil student
Noah Landgraf
Third year placement student from University of Manchester BSc in Developmental Biology
After completing his degree Noah went on to work as a Research Assistant in the lab of Dr. Neha Agrawal in University of Edinburgh.
Ioanna Pitsitianaki
Research Assistant
After two very successful and enjoyable years, Ioanna left the lab to persue a PhD in the lab of Dr. Anna Franz in UCL
Emily Howe
BMedSci Student
Joseph Delahunty
BMedSci Student
After a year of honing his dissection skills on adult Drosophila midguts, Joe has returned to his medical degree. Hopefully he will be able to put his new skills to good use...
We are currently looking for PhD applicants.
https://www.sheffield.ac.uk/bms/study/prospective_pg/projects/index
If you are interested in this, or in exploring other opportunities in the lab please get in touch with Kyra ([email protected]).
Mphil student
Noah Landgraf
Third year placement student from University of Manchester BSc in Developmental Biology
After completing his degree Noah went on to work as a Research Assistant in the lab of Dr. Neha Agrawal in University of Edinburgh.
Ioanna Pitsitianaki
Research Assistant
After two very successful and enjoyable years, Ioanna left the lab to persue a PhD in the lab of Dr. Anna Franz in UCL
Emily Howe
BMedSci Student
Joseph Delahunty
BMedSci Student
After a year of honing his dissection skills on adult Drosophila midguts, Joe has returned to his medical degree. Hopefully he will be able to put his new skills to good use...
We are currently looking for PhD applicants.
https://www.sheffield.ac.uk/bms/study/prospective_pg/projects/index
If you are interested in this, or in exploring other opportunities in the lab please get in touch with Kyra ([email protected]).
Department of Biomedical Sciences
University of Sheffield
Western Bank
Firth Court
Sheffield S10 2TN
University of Sheffield
Western Bank
Firth Court
Sheffield S10 2TN